Immunology

Immune system targets vitamin B12 pathway to neutralize bacteria

Close to 1.8 billion people worldwide are infected with Mycobacterium tuberculosis (Mtb), the common and occasionally deadly bacterium that causes millions of cases of tuberculosis each year. The bacteria, having coevolved ...

Medical research

Healthy, stress-busting fat found hidden in dirt

Thirty years after scientists coined the term "hygiene hypothesis" to suggest that increased exposure to microorganisms could benefit health, CU Boulder researchers have identified an anti-inflammatory fat in a soil-dwelling ...

Diseases, Conditions, Syndromes

Ancient Chinese malaria remedy artemisinin fights tuberculosis

A centuries-old herbal medicine, discovered by Chinese scientists and used to effectively treat malaria, has been found to potentially aid in the treatment of tuberculosis and may slow the evolution of drug resistance.

Diseases, Conditions, Syndromes

More than half of Amazonian armadillos carry leprosy

The bacteria that causes leprosy, a chronic disease that can lead to disfigurement and nerve damage, is known to be transmitted to humans from nine-banded armadillos. A new study in PLOS Neglected Tropical Diseases reports ...

Medications

New antibiotics could tackle drug-resistant tuberculosis bacteria

Infection by Mycobacterium tuberculosis kills 1.5 million people worldwide every year. Antibiotics to treat TB exist, but in recent years, multi-drug resistant (MDR), extensively drug-resistant (XDR) and totally drug-resistant ...

Medications

Why does tuberculosis find a 65-year-old drug so hard to resist?

Since its discovery in 1954, there have been almost no recorded cases of tuberculosis becoming resistant to the antibiotic drug D-cycloserine (DCS) in patients. With resistance to many other drugs on the rise, a team of ...

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