Page 19 - News tagged with myeloid leukemia

Medical research

Trial of gene therapy for sickle cell disease halted

A clinical trial of a new gene therapy for sickle cell disease that has shown promise has been halted after two participants were diagnosed with cancer.

Feb 24, 2021

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Oncology & Cancer

Researchers take early step toward leukemia drug therapy

A McMaster stem cell research team has made an important early step in developing a new class of therapeutics for patients with a deadly blood cancer.

Feb 16, 2021

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Oncology & Cancer

New classification of leukemia subtypes reveals potential of existing drugs

Using advanced RNA sequencing, scientists have identified two unique subtypes of a prominent mutation present in many patients with Acute Myeloid Leukemia (AML)—called NPM1—that could help predict survival and improve ...

Feb 16, 2021

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Oncology & Cancer

Gene network for leukemia factor

Transcription factors—proteins that regulate gene expression—play critical roles in cell fate decisions and are frequent targets of mutation in a variety of human cancers. Understanding how transcription factors contribute ...

Feb 5, 2021

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Oncology & Cancer

Larger panel finds more gene mutations, treatment targets for leukemia

A gene panel that looks for about 10 times the number of cancer-causing genes as panels currently used to diagnose and fine tune treatment for a variety of cancers is effective at identifying problematic genes in the most ...

Feb 1, 2021

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Medications

Metoclopramide inhibits proliferation of leukemia stem cells

A research team at Inselspital, Bern University Hospital and the University of Bern has identified and tested the use of an agent that can effectively inhibit the proliferation of leukemia stem cells. Metoclopramide (MPR), ...

Jan 27, 2021

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Medications

Investigational combo therapy shows benefit for TP53 mutant MDS and AML patients

Myelodysplastic Syndromes (MDS) and acute myeloid leukemia (AML) are rare hematologic malignancies of the bone marrow. They can occur spontaneously or secondary to treatment for other cancers, so called therapy related disease, ...

Jan 21, 2021

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Medical research

New drug combination shows promise as powerful treatment for AML

Scientists have identified two drugs that are potent against acute myeloid leukemia (AML) when combined, but only weakly effective when used alone. The researchers were able to significantly enhance cancer cell death by jointly ...

Jan 19, 2021

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Oncology & Cancer

Global trial reveals life saving drug for acute myeloid leukemia

A landmark paper published today in the New England Journal of Medicine describes the results from a global trial across 148 sites in 23 countries, showing a 30 percent improvement in survival in patients with acute myeloid ...

Dec 23, 2020

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