(HealthDay)—A polygenic score derived from pharmacogenomic evaluation of cytarabine (ara-C) pathway can help personalize treatment for pediatric patients with acute myeloid leukemia (AML), according to a study published ...
Feb 1, 2022
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Acute myeloid leukemia (AML) is an aggressive cancer of white blood cells with few effective targeted therapies available to treat it. Cold Spring Harbor Laboratory (CSHL) Professor Christopher Vakoc and former graduate student ...
Jan 11, 2022
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A unique collection of tissue samples donated by people with chronic myeloid leukemia was the driving force behind the discovery of a potentially major new treatment approach for drug-resistant leukemia. As published this ...
Dec 21, 2021
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An immunotherapy harnessing the immune system's "natural killer" cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return. Now, researchers at Washington University School of ...
Dec 14, 2021
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Mutations in the enzyme IDH (isocitrate dehydrogenase) are found in 15–20% of acute myeloid leukemia (AML) cases. IDH mutations have been shown to impact cellular differentiation and DNA and histone methylation, but little ...
Dec 13, 2021
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An international team has developed statistical models to predict the risk of early death in patients being treated with non-intensive therapies for acute myeloid leukemia (AML). Results of analyses using the models will ...
Dec 12, 2021
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A functional precision medicine study conducted in Finland demonstrates that treatment selection based on results from drug sensitivity testing of patients' cells can be clinically useful in patients with aggressive hematological ...
Nov 17, 2021
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Glasgow scientists have uncovered important information about how cancer cells become resistant to certain treatments, according to research published in Nature Communications.
Nov 17, 2021
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Researchers have made a huge leap forward in finding a targeted therapy for acute myeloid leukemia.
Nov 10, 2021
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Acute myeloid leukemia (AML) is the second most common leukemia diagnosed in children. It is hard to treat and can be fatal in some cases. While there have been some recent successes with genetically targeted therapies for ...
Nov 5, 2021
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