Oncology & Cancer

Milestone reached in new leukemia drug

Cold Spring Harbor Laboratory scientists, with chemists and cancer biologists from Dana-Farber Cancer Institute (DFCI), have developed a new therapy that extended the survival of mice with acute myeloid leukemia.

Oncology & Cancer

Gilteritinib superior in relapsed, refractory FLT3-mutated AML

(HealthDay)—For relapsed or refractory acute myeloid leukemia (AML) with mutations in the FMS-like tyrosine kinase 3 gene (FLT3), treatment with a selective FLT3 inhibitor, gilteritinib, results in significantly longer ...

Medications

Cocktail proves toxic to leukemia cells

A combination of drugs that affect mitochondria—the power plants inside cells—may become the best weapons yet to fight acute myeloid leukemia, according to Rice University researchers.

Oncology & Cancer

Pediatric cancers: Why some forms of leukemia only affect children

Acute myeloid leukemia (AML) mainly affects children, with often poor prognosis despite several decades of research into more effective treatments. A new study explains why some forms of leukemia develop in very young children ...

Oncology & Cancer

Blast count prognostic for CML presenting in advanced phase

(HealthDay)—Blast count seems to be the main prognostic count for patients with chronic myeloid leukemia (CML) presenting in an advanced phase, according to a study published online Aug. 27 in the American Journal of Hematology.

Oncology & Cancer

Leukemia drug shows promise for treating a childhood brain cancer

A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional ...

Oncology & Cancer

Many older patients with AML not receiving active treatment

(HealthDay)—Many older patients with acute myeloid leukemia (AML) do not receive any active treatment, and they have worse survival than those receiving active treatment, according to a study published online Sept. 4 in ...

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