A personalized method for testing the effectiveness of drugs that treat multiple myeloma may predict quickly and more accurately the best treatments for individual patients with the bone marrow cancer. The process, developed ...
Nov 20, 2015
0
19
Pevonedistat is a first-in-class, investigational small-molecule inhibitor of the NEDD8-activating enzyme, explained Shah. "This enzyme is part of the ubiquitin-proteasome system, which is the target of a number of FDA-approved ...
Nov 11, 2015
0
22
Researchers in the West Midlands have made a breakthrough in explaining how an incurable type of blood cancer develops from an often symptomless prior blood disorder. The findings could lead to more effective treatments and ...
Oct 16, 2015
0
21
Even patients with health insurance who have multiple myeloma may be vulnerable to "financial toxicity" – including those who make over $100,000 a year – because of the higher use of novel therapeutics and extended duration ...
Sep 30, 2015
0
11
Virtually all patients who develop myeloma have an asymptomatic disease called monoclonal gammopathy of undetermined significance (MGUS) in the years before the onset of myeloma. The five-year relative survival rate for myeloma ...
Sep 30, 2015
0
25
Even patients with health insurance who have multiple myeloma may be vulnerable to "financial toxicity" - including those who make over $100,000 a year - because of the higher use of novel therapeutics and extended duration ...
Sep 16, 2015
0
25
A study that used stored blood samples from U.S. Air Force personnel who conducted aerial herbicide spray missions of Agent Orange during the Vietnam war found a more than 2-fold increased risk of the precursor to multiple ...
Sep 3, 2015
0
7
(HealthDay)—In patients with newly diagnosed multiple myeloma, novel agent-based continuous therapy (CT) significantly improves progression-free survival and overall survival (OS) compared with fixed duration of therapy ...
Aug 31, 2015
0
14
In its first clinical trial, a breakthrough antibody therapy produced at least partial remissions in a third of patients with multiple myeloma who had exhausted multiple prior treatments, investigators at Dana-Farber Cancer ...
Aug 26, 2015
0
51
A new test for offers the possibility of near real time monitoring of bone diseases, such as osteoporosis and multiple myeloma. The functionality of the test, which measures changes in calcium isotope ratios, has been validated ...
Aug 17, 2015
0
51
