Neuroscience

First step to induce self-repair in the central nervous system

Damaged peripheral nerves can regenerate after an injury, for example, following a forearm fracture. Axons, the long projections of neurons that transmit stimuli or signals to other cells, are affected in the case of injury ...

Neuroscience

Perilous ruptures described in a multiple sclerosis model

The permanent neurological deficits of multiple sclerosis patients largely depend on the extent of degeneration of long nerve fibers. The latter is initiated by ruptures in the cell membrane and the resulting influx of calcium ...

Genetics

Gene therapy blocks peripheral nerve damage in mice

Nerve axons serve as the wiring of the nervous system, sending electrical signals that control movement and sense of touch. When axons are damaged, whether by injury or as a side effect of certain drugs, a program is triggered ...

Neuroscience

Discovery opens new opportunities to slow or reverse MS

Nerve cells stripped of their insulation can no longer carry vital information, leading to the numbness, weakness and vision problems often associated with multiple sclerosis. A new study shows an overlooked source may be ...

Neuroscience

Untangling the complex puzzle of optic nerve regeneration

The optic nerve is vital for vision—damage to this critical structure can lead to severe and irreversible loss of vision. Fengfeng Bei, PhD, a principal investigator in the Department of Neurosurgery at Brigham and Women's ...

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