Dopamine deficiency in the basal ganglia (a set of subcortical structures) causes severe motor dysfunctions, such as slowness of movements (bradykinesia), as observed in Parkinson's disease. Dopamine binds D1 and D2 receptors ...
Oct 6, 2015
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A German-French team has developed a light-sensitive switch that regulates a protein implicated in the neurobiology of synaptic plasticity. The agent promises to shed new light on the phenomenology of learning, memory and ...
Aug 28, 2015
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Activated neurons produce a protein that protects against nerve cell death. Prof. Dr. Hilmar Bading and his group at Heidelberg University's Interdisciplinary Center for Neurosciences have found out how this effect comes ...
Aug 24, 2015
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An international study led by scientists at McGill University reports, for the first time, that drugs that selectively target the melatonin MT2 receptor represent a novel class of analgesic drugs that could be used to treat ...
Feb 18, 2015
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Try putting an ice-cube in your mouth. The insides of your mouth and tongue instantly turn numb. Hold it in still and you will feel pain. Now try sucking on peppermint. The mint itself is at room temperature, but your mouth ...
Jan 22, 2015
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Dr. Uwe Schulte, Dr. Jochen Schwenk, Prof. Dr. Bernd Fakler, and their team have elucidated the enormous spatial and temporal dynamics in protein composition of the AMPA-type glutamate receptors, the most important excitatory ...
Oct 6, 2014
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Children who have been abused or neglected early in life are at risk for developing both emotional and physical health problems. In a new study, scientists have found that maltreatment affects the way genes are activated, ...
Jul 24, 2014
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A new study led by investigators at the Stanford University School of Medicine has implicated the blocking of endocannabinoids—signaling substances that are the brain's internal versions of the psychoactive chemicals in ...
Jun 18, 2014
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UT Southwestern Medical Center researchers have generated fresh insights that could aid in the development of rapid-acting antidepressants for treatment-resistant depression.
Jun 12, 2014
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Researchers at the University of California, San Diego School of Medicine have discovered that FDA-approved anti-psychotic drugs possess tumor-killing activity against the most aggressive form of primary brain cancer, glioblastoma. ...
Mar 7, 2014
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