Researchers at the Massachusetts General Hospital (MGH)/Harvard Medical School, Drs. Beste Kinikoglu and Yawei Kong, led by Dr. Eric C. Liao, cultured and characterized for the first time multipotent neural crest cells isolated ...
Feb 28, 2014
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Whitehead Institute researchers have created a new mouse-human modeling platform that could be used to study neural crest development as well as the modeling of a variety of diseases, including such cancers as melanoma and ...
Jan 25, 2016
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Neuroblastoma is the third most common type of tumour in children. Its aggressive nature and the frequency of metastatic disease at diagnosis contribute to the fact that neuroblastoma accounts for almost 15 per cent of childhood ...
Jan 25, 2016
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A group led by Associate Professor Makoto Ikeya has established a new method to generate mesenchymal stem cells (MSCs) from iPS cells via neural crest cells (NCCs) without animal-derived elements. It is expected to be used ...
Sep 28, 2022
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Mammalian embryonic development is an extremely complex and precise process. Specific molecular events act as cues that tell cells in the embryo where to move and what type to mature into. The expression levels of different ...
Apr 14, 2021
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Mutations in single genes can cause catastrophic diseases, such as Huntington's Disease or sickle cell anemia. However, many conditions, including cancer, diabetes and birth defects are multigenic, arising from the collective ...
Jan 31, 2013
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To grow or to specialise? To remain stationary or initiate migration? How do cells know what to do and how they should develop? The Hippo/YAP signalling pathway plays a crucial role when the cells of the neural crest – ...
Mar 22, 2016
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Mother cells from the adult carotid body can transform into blood vessels as well as neurons. This discovery could have important repercussions on the treatment of such diseases as pediatric tumors and Parkinson's.
May 19, 2017
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Several childhood cancer cell types show features of immature neural cells, and there is evidence suggesting that these tumors may arise from neural crest stem cells that underwent abnormal changes during embryonic development. ...
Feb 20, 2018
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(HealthDay)—The devastating mosquito-borne Zika virus can infect cells that play a role in skull development, a new study finds.
Sep 29, 2016
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