Progressive loss of neurons is the underlying cause for a diverse spectrum of severe diseases called neurodegenerative diseases, which include Parkinson's disease, amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa. ...
Apr 20, 2023
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When it comes to cell types, stem cells have unlimited potential—literally. These self-renewing cells, which are capable of giving rise to any cell type in the body, reside in specialized microenvironments known as niches. ...
Mar 15, 2023
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An exciting study from Texas Children's Hospital and Baylor College of Medicine has identified molecular biomarkers and two effective approaches to treat Infantile Neuroaxonal Dystrophy (INAD), a devastating and fatal pediatric ...
Feb 13, 2023
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In Down syndrome, the third copy of chromosome 21 causes a reorganization of the 3D configuration of the entire genome in a key cell type of the developing brain, a new study shows. The resulting disruption of gene transcription ...
Jan 6, 2022
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Our brain is extremely complex, performing countless complicated processes that allow us to think, move and feel. This is only possible because of the enormous diversity of different cell types in the brain, each with a very ...
Dec 20, 2021
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A novel therapy engineered by Northwestern Medicine investigators improved progression-free and overall survival for patients with newly diagnosed malignant gliomas, according to results from a recent phase I clinical trial ...
Jul 30, 2021
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Researchers at the University of Maryland School of Medicine (UMSOM) have for the first time identified stem cells in the region of the optic nerve, which transmits signals from the eye to the brain. The finding, published ...
Jul 31, 2020
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Autism has long been associated only with behavioral and environmental factors, but the role of genetics in its development is now increasingly evident. Some 100 genes have been found to play a role in autism spectrum disorder, ...
May 15, 2020
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A study by researchers at the UCLA Jonsson Comprehensive Cancer Center has identified a possible new drug that could help prevent cognitive decline in people who undergo radiation therapy for brain tumors. The researchers ...
Apr 15, 2020
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When brains begin developing, there are a lot of moving parts—and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism. But scientists don't know much about the ways that ...
Mar 11, 2020
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