A Massachusetts General Hospital (MGH)-led research team has found that a defect in transcription of the TAF1 gene may be the cause of X-linked dystonia parkinsonism (XDP), a rare and severe neurodegenerative disease. The ...
Feb 22, 2018
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A promising strategy for helping stroke patients recover, transplanting neural progenitor cells to restore lost functions, asks a lot of those cells. They're supposed to know how to integrate into a mature (but damaged) brain. ...
Jul 1, 2019
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Creating induced pluripotent stem cells or iPS cells allows researchers to establish "disease in a dish" models of conditions ranging from Alzheimer's disease to diabetes. Scientists at Yerkes National Primate Research Center ...
Sep 5, 2014
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Four months after treating them, Yasuhiro Shiga, MD, Ph.D., checked on his rats. Walking into the lab, he carried minimal expectations. Treating spinal cord injuries with stem cells had been tried by many people, many times ...
Dec 17, 2019
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A novel therapy engineered by Northwestern Medicine investigators improved progression-free and overall survival for patients with newly diagnosed malignant gliomas, according to results from a recent phase I clinical trial ...
Jul 30, 2021
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Glial cells – a family of cells found in the human central nervous system and, until recently, considered mere "housekeepers" – now appear to be essential to the unique complexity of the human brain. Scientists reached ...
Mar 7, 2013
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Johns Hopkins researchers have begun to connect the dots between a schizophrenia-linked genetic variation and its effect on the developing brain. As they report July 3 in the journal Cell Stem Cell, their experiments show ...
Jul 3, 2014
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esearchers from Hokkaido University in Japan together with an international team of scientists implanted specialized embryonic stem cells into the severed spinal cords of rats. The stem cells, called neural progenitor cells, ...
Apr 11, 2016
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In Down syndrome, the third copy of chromosome 21 causes a reorganization of the 3D configuration of the entire genome in a key cell type of the developing brain, a new study shows. The resulting disruption of gene transcription ...
Jan 6, 2022
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(Medical Xpress)—Researchers in China have developed a technique for reprogramming cells found in urine into neural progenitor cells that are capable of growing into neurons. In their paper published in Nature Methods, ...
