Researchers at the University of California, Davis, have found a link between traffic-related air pollution and an increased risk for changes in brain development relevant to neurodevelopmental disorders. Their study, based ...
Jun 17, 2020
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Physicians and scientists are constantly on the lookout for new disease genes that can help them understand why patients have undiagnosed medical problems. Often the first clues come from genetic testing that reveals a change ...
Nov 23, 2020
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The human genome contains over 4.5 million sequences of DNA called "transposable elements," virus-like entities that "jump" around and help regulate gene expression. They do this by binding transcription factors, which are ...
Aug 31, 2020
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Neurodevelopmental disorders (NDD) encompass highly prevalent conditions such as autism and epilepsy, with cognitive disabilities alone affecting 1-3% of the global population. Developmental epileptic encephalopathies (DEE) ...
Dec 16, 2022
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Researchers have recently begun to realize that biological sex plays a key role in disease risk. Sex plays a role in hypertension, diabetes, arthritis—and in many neurological and psychiatric disorders. Depression and anxiety ...
Jul 3, 2018
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Geneticists discovered a molecular trigger for a severe autism-related disorder that has enabled them to start testing a potential therapy targeting a specific protein in the brain.
Feb 11, 2019
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Brain development consists of a sequence of coordinated steps, which are mainly instructed by our genes. During these steps, the proper positioning and functionality of nerve cells in the brain (neurons) are critical—nonfunctional ...
Mar 29, 2023
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Prenatal exposure to topiramate, valproate, and certain duotherapies is associated with increased risks for autism spectrum disorder (ASD) and intellectual disability (ID), according to a study published online May 31 in ...
May 31, 2022
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Emerging evidence implicates the gut microbiome in cognitive outcomes and neurodevelopmental disorders, but the influence of gut microbial metabolism on typical neurodevelopment has not been explored in detail. Researchers ...
Dec 27, 2023
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Many neurodevelopmental disorders such as epilepsy, schizophrenia, and autism have been linked to disruption of the key neurotransmitter GABA, but the underlying causes of the disruptions have been difficult to pinpoint. ...
Oct 17, 2019
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