Alzheimer's disease affects more than 35 million people, a number that is expected to increase in the coming years. Currently, Alzheimer's diagnoses rely on clinical neuropathologic assessment of amyloid-β (Aβ) peptide ...
Dec 7, 2016
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Early stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cells and the degeneration of these cells. For most diseases, this selective vulnerability pattern ...
Mar 11, 2024
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Tangled up brain fibrils made up of a rogue protein known as tau are the hallmark of Alzheimer's disease (AD) that likely hold the key to treatments, making them of great interest to researchers. Mimicking the formation and ...
Nov 16, 2016
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Writing in the April 11 issue of the Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells ...
Apr 11, 2016
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A panel of 48 proteins in the cerebrospinal fluid (CSF 48 panel) complements existing CSF biomarkers for Alzheimer disease (AD), according to a study published in the Sept. 6 issue of Science Translational Medicine.
Sep 8, 2023
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A PET image using F-18 THK5117, a novel tracer that labels neurofibrillary tangles with high selectivity, has been selected as the Society of Nuclear Medicine and Molecular Imaging's (SNMMI) 2014 Image of the Year. Researchers ...
Jun 10, 2014
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On Jan. 31, aducanumab, a pricey drug approved for treatment of early-stage Alzheimer's disease, was withdrawn from the market. And in early March, the Food and Drug Administration delayed its decision regarding whether to ...
Mar 14, 2024
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Researchers from Boston University School of Medicine (BUSM) report variants in a new gene, PLXNA4, which may increase the risk of developing Alzheimer's disease (AD). The discovery of this novel genetic association may lead ...
Jul 28, 2014
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