Alzheimer's disease & dementia

PET points to tau protein as leading culprit in Alzheimer's

Alzheimer's is a devastating and incurable disease marked by beta-amyloid and tau protein aggregations in the brain, yet the direct relationship between these proteins and neurodegeneration has remained a mystery. New molecular ...

Neuroscience

Neural networks learn to link temporally dispersed stimuli

Rustling leaves, a creaking branch: To a mouse, these sensory impressions may at first seem harmless - but not if a cat suddenly bursts out of the bush. If so, they were clues of impending life-threatening danger. Robert ...

Medical research

Astrocytes derived from patients with bipolar disorder malfunction

Brain cells called astrocytes derived from the induced pluripotent stem cells of patients with bipolar disorder offer suboptimal support for neuronal activity. In a paper appearing March 4th in the journal Stem Cell Reports, ...

Neuroscience

Culturing the connectome

Mapping the human brain's network of interconnections, known as the connectome is typically done with help from computational tools because recreating interconnections between different brain regions has been challenging ...

Diseases, Conditions, Syndromes

Discovery of novel mechanisms that cause migraines

Researchers at CNRS, Université Côte d'Azur and Inserm have demonstrated a new mechanism related to the onset of migraine. They found how a mutation that causes dysfunction in a protein which inhibits neuronal electrical ...

Neuroscience

New fluorescent protein permanently marks neurons that fire

A new tool developed at the Howard Hughes Medical Institute's Janelia Research Campus lets scientists shine a light on an animal's brain to permanently mark neurons that are active at a particular time. The tool—a fluorescent ...

Neuroscience

Finding thoughts in speech

For the first time, neuroscientists were able to find out how different thoughts are reflected in neuronal activity during natural conversations. Johanna Derix, Olga Iljina and the interdisciplinary team of Dr. Tonio Ball ...

page 30 from 40