Mutations in the gene ANT1 may confer a risk for bipolar disorder through a complex interplay between serotonin and mitochondrial signaling in the brain. These two pathways have been separately implicated in bipolar disorder, ...
Jun 11, 2018
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A team of scientists led by Darío Acuña-Castroviejo, professor at the University of Granada (UGR), has published the results of a new breakthrough in molecular mechanisms of the anti-Parkinsonian activity of melatonin.
Jan 11, 2018
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Increased activity of the hormone, kisspeptin, enhances sexual attraction and decreases anxiety in male mice, according to new research presented today at the Society for Endocrinology annual conference in Harrogate. The ...
Nov 5, 2017
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A study published in the journal Nature Neuroscience describes the identification of a novel molecular pathway that can constitute a therapeutic target for cognitive defects in Parkinson's disease. The study showed that abnormal ...
Sep 26, 2017
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It was when Xinglong Wang, PhD, received a call from a desperate father of a middle-aged son with amyotrophic lateral sclerosis (ALS) that he realized the extraordinary importance of his work. "Can you help save my son's ...
Jan 23, 2017
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Age-related dementia will affect 10 percent of people in the U.S. within their lifetime.
Nov 10, 2016
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Charcot-Marie-Tooth disease is an inherited disorder that leads to a gradual loss of motor neurons and, eventually, paralysis. The condition is caused by genetic mutations that disrupts cells' energy factories, called mitochondria. ...
Oct 24, 2016
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Alzheimer's is a devastating and incurable disease marked by beta-amyloid and tau protein aggregations in the brain, yet the direct relationship between these proteins and neurodegeneration has remained a mystery. New molecular ...
Jun 13, 2016
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(Medical Xpress)—A team of researchers working in Germany has found that giving two different types of amyloid-β antibodies to mice genetically engineered to have Alzheimer's type symptoms caused them to develop a type ...
A new study from the Gladstone Institutes shows for the first time that impairments in mitochondria—the brain's cellular power plants—can deplete cellular energy levels and cause neuronal dysfunction in a model of neurodegenerative ...
Sep 14, 2015
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