Charcot-Marie-Tooth disease is an inherited disorder that leads to a gradual loss of motor neurons and, eventually, paralysis. The condition is caused by genetic mutations that disrupts cells' energy factories, called mitochondria. ...
Oct 24, 2016
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For the first time, scientists found that in spinal muscular atrophy (SMA), the affected nerve cells that control muscle movement, or motor neurons, have defects in their mitochondria, which generate energy used by the cell. ...
Sep 15, 2016
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The spike in blood sugar levels that can come after a meal is controlled by the brain's neuronal mitochondria, which are considered the "powerhouse of cells," Yale School of Medicine researchers found in a new study.
Feb 25, 2016
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A new study from the Gladstone Institutes shows for the first time that impairments in mitochondria—the brain's cellular power plants—can deplete cellular energy levels and cause neuronal dysfunction in a model of neurodegenerative ...
Sep 14, 2015
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A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If it cannot, the defective components pile up and the cell becomes sick ...
Aug 12, 2015
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Researchers have discovered a thick band of microtubules in certain neurons in the retina that they believe acts as a transport road for mitochondria that help provide energy required for visual processing. The findings appear ...
Jun 29, 2015
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Although natural selection is often thought of as a force that determines the adaptation of replicating organisms to their environment, Harvard researchers have found that selection also occurs at the level of neurons, which ...
Feb 26, 2015
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A new study by researchers at the University of Utah School of Medicine sheds light on a longstanding question about the role of mitochondria in debilitating and fatal motor neuron diseases and resulted in a new mouse model ...
Sep 19, 2014
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The failing in the work of nerve cells: An international team of researchers led by Prof. Dr. Chris Meisinger from the Institute of Biochemistry and Molecular Biology of the University of Freiburg has discovered how Alzheimer's ...
Aug 29, 2014
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Researchers at King's College London have discovered how a molecular 'scaffold' which allows key parts of cells to interact, comes apart in dementia and motor neuron disease, revealing a potential new target for drug discovery.
Jun 3, 2014
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