Medications

Study sheds new light on a promising antidepressant

Ketamine, a well-known anesthetic used in smaller doses as a party drug, was hailed as a "new hope for depression" in a Time magazine cover story in 2017. Two years later, the arrival of the first ketamine-based antidepressant—the ...

Neuroscience

How the brain interprets motion while in motion

Imagine you're sitting on a train. You look out the window and see another train on an adjacent track that appears to be moving. But, has your train stopped while the other train is moving, or are you moving while the other ...

Neuroscience

How the brain knows when to take out the trash

The brain has its own housekeeping service, a sophisticated mechanism that cleans up debris that is left over from cellular activity. But scientists have had a hard time figuring out exactly how the brain knows when to initiate ...

Genetics

Gene therapy boosts Parkinson's disease drug benefits

In late-stage Parkinson's disease, the drug levodopa becomes less effective in treating symptoms because of the inexorable loss of dopamine-releasing neurons. But a new Northwestern Medicine preclinical study shows a gene ...

Neuroscience

Researchers observe memory formation in real time

Why is it that someone who hasn't ridden a bicycle in decades can likely jump on and ride away without a wobble, but could probably not recall more than a name or two from their 3rd grade class?

Neuroscience

Team discovers novel root cause of tau-induced neurodegeneration

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) today reported the discovery of a novel mechanism by which pathological forms of tau protein cause neurons to die. Alzheimer's ...

Medical research

Calcium: A key player for a promising and safe brain treatment?

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)—specialized molecules that can modulate RNA and alter protein production—directly injected into the cerebrospinal fluid, in ...

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