Neuroscience

Dieting: Brain amplifies signal of hunger synapses, finds study

Many people who have dieted are familiar with the yo-yo effect: after the diet, the kilos are quickly put back on. Researchers from the Max Planck Institute for Metabolism Research and Harvard Medical School have now shown ...

Genetics

New insights into the origins of spinal muscular atrophy

Columbia researchers have discovered how a genetic defect leads to spinal muscular atrophy (SMA), a critical piece of information about the disease that neurologists have been seeking for decades.

Neuroscience

'Spatial Computing' enables flexible working memory

Routine tasks that require working memory, like baking, involve remembering both some general rules (e.g. read the oven temperature and time from the recipe and then set them on the oven) and some specific content for each ...

Medical research

Calcium: A key player for a promising and safe brain treatment?

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)—specialized molecules that can modulate RNA and alter protein production—directly injected into the cerebrospinal fluid, in ...

Neuroscience

How to generate new neurons in the brain

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence to proliferation is still poorly understood. ...

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