A typical Western high-fat diet can increase the risk of painful disorders common in people with conditions such as diabetes or obesity, according to a groundbreaking paper authored by a team led by The University of Texas ...
Jun 23, 2021
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One of the hallmarks of chronic pain is inflammation, and scientists at the UNC School of Medicine have discovered that anti-inflammatory cells called MRC1+ macrophages are dysfunctional in an animal model of neuropathic ...
Mar 4, 2021
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Three decades-old antibiotics administered together can block a type of pain triggered by nerve damage in an animal model, UT Southwestern researchers report. The finding, published online today in PNAS, could offer an alternative ...
Feb 22, 2021
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Researchers at McGill University have discovered that a protein found in the membrane of our sensory neurons are involved in our capacity to feel mechanical pain, laying the foundation for the development of powerful new ...
Feb 24, 2020
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University at Buffalo researchers who previously discovered how chronic neuropathic pain arises in the brain have now developed a treatment to block it.
Sep 16, 2019
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Sortilin, which is a protein expressed on the surface of nerve cells, plays a crucial role in pain development in laboratory mice—and in all likelihood in humans as well. This is the main conclusion of the study "Sortilin ...
Jun 20, 2019
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Facing an urgent need for safer and more effective therapies for those suffering from debilitating pain in the midst of an opioid crisis, Saint Louis University researchers are on a mission to find a non-narcotic off-switch ...
May 9, 2019
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In animal models of a totally crushed peripheral nerve, the damaged axons are broken down, allowing healthy ones to regrow. But humans rarely suffer complete axonal damage. Instead, axons tend to be partially damaged, causing ...
Jan 31, 2019
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A study led by Boston Children's Hospital and the National Institute of Mental Health (NIMH) may open up new opportunities for treating neuropathic pain, a difficult-to-treat type of chronic pain due to damage to the nervous ...
Sep 12, 2018
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Researchers at University of California San Diego School of Medicine have found a new way to block a root cause of pain. The key is a naturally occurring protein called apolipoprotein A-I binding protein (AIBP). AIBP binds ...
May 29, 2018
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