Diseases, Conditions, Syndromes

When sequencing fails to pinpoint a rare disease

Routine sequencing has given unprecedented insight into the genetics of rare diseases, but genomics fails to diagnose up to half of patients who are tested. That's the problem German scientists tackled in a recent study in ...

Cancer

The role of immune cells in the formation of metastases

Tumor cells use a certain type of immune cell, so-called neutrophils, to enhance their ability to form metastases. Scientists from the University of Basel and the University Hospital of Basel have deciphered the mechanisms ...

Cardiology

Myocarditis: Overshooting the mark

Researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich have shown that a protein called midkine, a member of the class of signaling molecules known as cytokines, is a key driver of inflammation in the heart muscle ...

Inflammatory disorders

A new mechanism in the control of inflammation

After infection or tissue injury, the inflammatory immune response attacks the infection and repairs the damaged tissue. However, sometimes excess inflammation can have the opposite effect, increasing injury in a process ...

Cancer

Function of neutrophils during tumor progression unraveled

Researchers at The Wistar Institute have characterized the function of neutrophils, a type of white blood cells, during early stages of tumor progression, showing that they migrate from the bone marrow to distant sites and ...

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