Medical research

To treat rare disease, NIH scientists repurpose FDA-approved drug

A new study reports that a drug already approved by the Food and Drug Administration for use in patients undergoing a bone marrow transplant may also have promise for treating people who have a rare immune deficiency known ...

Immunology

Researchers find elusive source of most abundant immune cell

Neutrophils—short-lived, highly mobile and versatile—outnumber all other immune cells circulating through the blood stream. Yet, despite the cells' abundance, the progenitor cell that only gives rise to neutrophils had ...

Inflammatory disorders

White blood cell enzyme contributes to inflammation and obesity

Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered that an imbalance between ...

Ophthalmology

Antibodies to immune cells protect eyes in pseudomonas infection

Contact lenses, particularly the extended wear variety, render wearers vulnerable to eye infections from Pseudomonas aeruginosa. These infections can cause severe damage, including blindness. Treating the eye with antibodies ...

Medical research

Research group identifies potential therapeutic target for lupus

A recent study published in JCI found that a neutrophil's endoplasmic reticulum, the organelle that normally makes proteins in the cell, becomes stressed in the autoimmune disorder lupus. This stress activates a molecule ...

Medical research

Rogue blood cells may contribute to post-surgery organ damage

A study from scientists at Queen Mary, University of London, sheds new light on why people who experience serious trauma or go through major surgery, can suffer organ damage in parts of the body which are seemingly unconnected ...

Immunology

How immune cells move against invaders

UCSF scientists have discovered the unexpected way in which a key cell of the immune system prepares for battle. The finding, they said, offers insight into the processes that take place within these cells and could lead ...

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