Oncology & Cancer

Could neutrophils be the secret to cancer's Achilles' heel?

A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body's own immune system can eliminate cancer cells without damaging host cells. The findings have the potential to develop ...

Medical research

Research group identifies potential therapeutic target for lupus

A recent study published in JCI found that a neutrophil's endoplasmic reticulum, the organelle that normally makes proteins in the cell, becomes stressed in the autoimmune disorder lupus. This stress activates a molecule ...

Oncology & Cancer

Lung cancer resistance: the key is glucose

Cancers are not only made of tumor cells. In fact, as they grow, they develop an entire cellular ecosystem within and around them. This "tumor microenvironment" is made up of multiple cell types, including cells of the immune ...

Oncology & Cancer

Priming the immune system to attack cancer

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, ...

Medical research

The unexpected repair function of neutrophils

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered that neutrophils, the most abundant cells of the innate immune system, have many more functions in the body than previously thought. ...

Immunology

Cells sacrifice themselves to boost immune response to viruses

Whether flu or coronavirus, it can take several days for the body to ramp up an effective response to a viral infection. New research appearing in the journal Nature Immunology describes how different cells in the immune ...

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