New drugs are often used not only for one disease (first approved indication) but also for other diseases (supplemental indications).
Jul 5, 2023
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New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease. The study found that a protein known to be active in immune ...
Jul 5, 2023
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Mutations in the KRAS gene are the major driver of pancreatic cancer. The resulting protein controls multiple signaling pathways involved in cell growth and survival. In cancer, the gene is mutated to be permanently "on," ...
Jun 29, 2023
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Scientists have identified nine genes that play a key role in increasing the risk of developing type 1 diabetes. Only four of the genes identified have previously been linked to type 1 diabetes in humans. Experts say the ...
Jun 14, 2023
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Contrary to expectations, the risk for relapses, overdoses and deaths related to substance use disorder didn't increase after a large-scale prison release in New Jersey, according to a Rutgers study.
Jun 2, 2023
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Researchers at Wilmer Eye Institute, Johns Hopkins Medicine say they have evidence that an experimental drug may prevent or slow vision loss in people with diabetes. The results are from a study that used mouse as well as ...
May 25, 2023
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The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.
May 23, 2023
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Reforms to New Jersey's Medicaid program successfully spurred ongoing increases in buprenorphine prescriptions for the treatment of opioid addiction, according to a Rutgers analysis.
May 19, 2023
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Inflammation is a complex biological process that can eradicate pathogens and promotes repair of damaged tissues. However, deregulation of the immune system can lead to uncontrolled inflammation and produce lesions instead. ...
Apr 27, 2023
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Modern drugs can be very effective at treating cancer and have led to greatly improved survival rates. However, some cancer treatments can cause damage to the heart, or cardiotoxicity. This damage can present in a range of ...
Apr 27, 2023
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