CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway. However, ...
Jun 12, 2024
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Immunotherapy is one of the pillars in the fight against cancer and aims to enable the body's own immune system to fight a tumor. A recent study now shows that removing certain enzymes that regulate epigenetic processes from ...
Jun 7, 2024
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An international research team led by scientists from the University of Liège has discovered an interesting new therapeutic target for the treatment of melanoma resistant to targeted therapies. Inhibition of the VARS enzyme ...
Jun 7, 2024
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An international study led by Dr. Li Qi-Jing from the Agency for Science, Technology and Research (A*STAR) has revealed a mechanism by which melanoma, the most aggressive form of skin cancer, evades the immune system.
May 9, 2024
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Researchers from the UAB have identified a region in the early aggregates of the alpha-synuclein protein that can be targeted to prevent its conversion into the toxic amyloid fibrils that accumulate in the brains of people ...
May 6, 2024
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In a development in cancer research, scientists are exploring new therapeutic strategies that move beyond traditional cytotoxic treatments, which have historically targeted uncontrolled cell proliferation.
Apr 30, 2024
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Spinal muscular atrophy, or SMA, is the leading genetic cause of infant death. Less than a decade ago, Cold Spring Harbor Laboratory (CSHL) Professor Adrian Krainer showed this brutal disease can be treated by tweaking a ...
Mar 6, 2024
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The importance of lipids as one of the fundamental biological compounds is well established as they are important signaling molecules and key components of metabolic disorders. The imbalance in lipid homeostasis and the dysregulation ...
Glioblastoma is the most common type of brain tumor that affects adults and, unfortunately, still remains incurable. In a new study, researchers have demonstrated that a specific mitochondrial protein plays an important role ...
Oct 17, 2023
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B-cell acute lymphoblastic leukemia (B-ALL) is one of the most common forms of childhood cancer. The overall survival rate is more than 80%, but not in all subtypes; in leukemia with the highest incidence among infants, in ...
Sep 27, 2023
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