The golden road to pharmaceutical riches can quickly become a rocky wilderness trail. Chemical compounds that hit a target in the lab often fall short in human studies.
Dec 13, 2023
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Mechanical thrombectomy (MT) is safe and effective in real-world, high-risk patients with pulmonary embolism (PE), according to a study published online Oct. 31 in the Journal of the Society for Cardiovascular Angiography ...
Dec 10, 2023
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For patients with atrial fibrillation, ischemic strokes (IS) are less often fatal or disabling with left atrial appendage closure (LAAC) prophylaxis than with direct oral anticoagulant (DOAC) prophylaxis, according to a study ...
Dec 6, 2023
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For patients with hormone receptor (HR)-positive HER2-mutant metastatic breast cancer (MBC) with progression on cyclin-dependent kinase 4/6 inhibitor (CDK4/6i) therapy, neratinib + fulvestrant + trastuzumab (N + F + T) is ...
Nov 29, 2023
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Adults with low household income are less likely to have a cardiologist involved in their care during hospitalization for heart failure than adults with higher incomes, according to a study published online Nov. 20 in JAMA ...
Nov 21, 2023
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Neuromelanin-sensitive magnetic resonance imaging (NM-MRI) contrast is associated with psychosis severity in antipsychotic-free patients with schizophrenia, according to a study published online Nov. 8 in JAMA Psychiatry.
Nov 21, 2023
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Were lockdowns an effective response to COVID-19 or would it have been better to limit intervention and let individuals spontaneously reduce their own risk of infection? Three years on from the public health emergency that ...
Nov 20, 2023
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Burnout has increased among anesthesiologists since the start of the COVID-19 pandemic in 2020, according to a study published in the November issue of Anesthesiology.
Nov 15, 2023
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An analysis co-led by a Brown public health researcher has found that the nation's first two government-sanctioned overdose prevention centers were not associated with significant changes in crime.
Nov 13, 2023
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Coadministration of the BNT162b2 BA.4/5 bivalent mRNA COVID-19 vaccine (BNT162b2-biv) and seasonal influenza vaccine (SIV) generally has similar effectiveness against COVID-19- and SIV-related outcomes compared with administration ...
Nov 9, 2023
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