Oncology & Cancer

New signaling pathway linked to breast cancer metastasis

Lymph nodes help to fight off infections by producing immune cells and filtering foreign materials from the body, such as bacteria or cancer cells. Thus, one of the first places that cancer cells are found when they leave ...

Immunology

Lymph nodes with location memory

Regulatory T cells (or "Tregs" for short) play a central role in the human immune system: They guide all of the other immune cells and make sure they are tolerant of the body's own cells and harmless foreign substances. How ...

Immunology

Bone marrow backup needed to tackle respiratory infections

Scientists at the Francis Crick Institute have found how the immune system triggers an 'emergency' dendritic cell response during infection, with dendritic cells at the site of infection being reinforced by new cells which ...

Immunology

Lymph node structural cells rein in human immune responses

Until now, the study of the immune system has focused almost exclusively on white blood cells, and T cells in particular, as the body's major infection fighters. However, new research published September 4th in the open access ...

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