Dendritic cells (DCs) are one of our bodies' first line of defense against invaders, and are stationed like sentinels at all outer and inner surfaces as well as in most of our organs. When they detect something foreign, they ...
May 18, 2020
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After a patient is diagnosed with lymphoma—an often-treatable type of cancer that attacks the lymph nodes, spleen, thymus, bone marrow and more—the natural next steps are determining the patient's survival outlook and ...
Oct 4, 2019
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143
A combination of two drugs keeps patients with chronic lymphocytic leukemia disease-free and alive longer than the current standard of care, according to a phase-3 clinical trial of more than 500 participants conducted at ...
Jul 31, 2019
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108
Immune checkpoint blockade (ICB) therapy using the antibody that combats the programmed cell death ligand 1 (PD-L1) shows great potential and is causing a revolution in clinical cancer management. Unfortunately, only a subset ...
Jul 12, 2019
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126
A promising new way to treat some types of cancer is to program the patient's own T cells to destroy the cancerous cells. This approach, termed CAR-T cell therapy, is now used to combat some types of leukemia, but so far ...
Jul 11, 2019
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256
As food enters the intestine, it embarks on windy, lengthy journey. For most of the route, its surroundings don't appear to change much. But new research from Rockefeller's Daniel Mucida shows that the food-processing canal ...
May 24, 2019
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Researchers have gained a greater understanding of the biology of staphylococcus skin infections in mice and how the mouse immune system mobilizes to fight them. A study appears this week in the PNAS. Community acquired methicillin-resistant ...
May 15, 2019
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A new HIV vaccine delivery strategy appears to enhance the protective immune response in a preclinical model. Scientists at the La Jolla Institute for Immunology (LJI) have discovered that delivering an HIV vaccine in small ...
May 9, 2019
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113
Immunotherapy drugs known as checkpoint inhibitors have revolutionized cancer treatment: many patients with malignancies that until recently would have been considered untreatable are experiencing long-term remissions. But ...
Apr 4, 2019
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213
Only a few vaccines—for example, against polio and rotavirus—can be given orally. Most must be delivered by injection. Weizmann Institute of Science researchers suggest this may be, in part, because the training program ...
Mar 4, 2019
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