Medical research

In the liver, a stressed cell can be bad news for its neighbors

A key protein in the communication channels between cells can allow a stress response in one liver cell to spread to neighboring liver cells in mice, causing otherwise healthy cells to become dysfunctional, according to new ...

Diseases, Conditions, Syndromes

Why severe fatty liver leads to liver damage

In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes ...

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