Significant improvement in progression free survival and response rate combined with reduced symptoms and better quality of life are reported as outcomes of a new treatment approach for patients with desmoid tumors, which ...
Sep 12, 2022
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Natural killer cells (NK cells), play an important role in the body's defences against cancer and infections. Now, in a joint project, researchers at Lund University in Sweden, the University of Oxford, and Karolinska Institutet ...
Dec 14, 2018
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Researchers in Germany have discovered that colon cancers are often resistant to existing drug treatments because they are composed of two different cell types that can replace each other when one cell type is killed. The ...
May 16, 2018
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Investigators at Vanderbilt-Ingram Cancer Center (VICC) and the Virginia Tech Carilion Research Institute (VTCRI) have revealed a gene mutation's role in Von Hippel-Lindau syndrome, a genetically inherited disease which causes ...
Mar 12, 2018
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EPFL spin-off Cellestia Biotech has just been given the regulatory go-ahead to start clinical testing a molecule it has developed to treat cancers involving mutations of the Notch gene. The molecule is a ray of hope for the ...
Sep 1, 2017
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Rafal Ciosk and his group at the FMI have identified an important link between the Notch signaling pathway and PRC2-mediated gene silencing. They showed that a fine balance between epigenetic silencing and signaling is crucial ...
Sep 23, 2016
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A new research report appearing in the August 2016 issue of the Journal of Leukocyte Biology reveals a potentially new therapeutic target for preventing or stopping preterm labor. Specifically, using mice, researchers from ...
Aug 1, 2016
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A recent study led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, in collaboration with the Univerity of Maryland School of Pharmacy and StemSynergy Therapeutics, ...
Jun 15, 2016
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A new study by Johns Hopkins researchers links a well-known cell communication pathway called Notch to one of the most common—but overall still rare—brain tumors found in children.
Feb 6, 2015
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Notch genes are a double-edged sword: in some cancers they have a harmful effect because they promote tumour growth, whilst in others they act as tumour suppressors. The reason is still unclear, making it impossible to predict ...
Jan 12, 2015
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