The characteristics of acceptable preapproval evidence were more flexible for novel drugs approved by the U.S. Food and Drug Administration in 2020, according to a research letter published online May 17 in JAMA Network Open.
May 18, 2022
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Inhibition of Ubiquitin Specific Peptidase 47 (USP47) was identified as a novel therapeutic target for hematologic malignancies bearing mutant oncoprotein EZH2, according to scientists from the Hefei Institutes of Physical ...
Jan 27, 2022
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Early 2020 saw the world break into what has been described as a "war-like situation": A pandemic, caused by the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), the likes of which majority of the living ...
Jul 1, 2021
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A Yale-led study reveals that new medicines and vaccines approved for use in the United States are often unavailable in countries that hosted their clinical trials, suggesting that the benefits of drug research are not being ...
May 6, 2021
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If Priscila Medina had gotten COVID-19 a year ago, she would have had no treatments proven safe and effective to try. But when the 30-year-old nurse arrived at a Long Island hospital last month, so short of breath she could ...
Apr 26, 2021
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A novel drug almost entirely cleared moderate to severe psoriasis in over 60% of the patients who took part in two phase three clinical trials of a new drug.
Apr 26, 2021
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Researchers from the National Institutes of Health have identified and tested a drug combination that exploits a weakness in small cell lung cancer (SCLC), an aggressive, dangerous cancer. The scientists targeted a vulnerability ...
Apr 12, 2021
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A Hong Kong Baptist University-led (HKBU) research team has developed a novel drug which has the potential to become a next-generation treatment for cancers associated with Epstein-Barr virus (EBV).
Mar 2, 2021
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Scientists at Northwestern Medicine have developed a novel therapy to trick cancer cells into gobbling up what they think is their favorite food—cholesterol—which actually triggers their destruction. What appears to them ...
Jan 26, 2021
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Dr. Lisa Philp and Professor Colleen Nelson, from the QUT Faculty of Health's School of Biomedical Science, are developing drugs to fight advanced prostate cancer that could also prevent and or treat acute respiratory distress ...
Nov 16, 2020
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