A UT Southwestern research team has cataloged gene activity in the skeletal muscle of mice, comparing healthy animals to those carrying a genetic mutation that causes Duchenne muscular dystrophy (DMD) in humans. The findings, ...
Dec 21, 2020
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Usually, each cell has exactly one nucleus. But the cells of our skeletal muscles are different: These long, fibrous cells have a comparatively large cytoplasm that contains hundreds of nuclei. But up to now, we have known ...
Dec 11, 2020
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There is an extremely high probability that individuals with 22q11.2 micro deletion syndrome—a rare genetic disorder—will develop schizophrenia together with one of its most common symptoms, auditory hallucinations. Scientists ...
May 26, 2020
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The old adage "use it or lose it" tells us: if you stop using your muscles, they'll shrink. Until recently, scientists thought this meant that nuclei—the cell control centers that build and maintain muscle fibers—are ...
Jan 25, 2019
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A multidisciplinary study led by BCBL, a Basque research centre, opens the door to the investigation of the structure and functions of human thalamic nuclei and their involvement in Alzheimer's, dyslexia, epilepsy, Huntington's ...
Nov 20, 2018
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An interdisciplinary team of researchers has identified a new gene linked to human aortic aneurysms. By combining comprehensive genetic studies in the fruit fly, dataset searches and analysis of diseased human aortic tissue, ...
Apr 24, 2018
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Children who suffer from Hutchinson-Gilford Progeria syndrome age prematurely due to a defective protein in their cells. Scientists at Technische Universität München have now identified another important pathological factor: ...
Dec 17, 2014
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In pathology, cells and cell nuclei are usually examined using a microscope for bio-marker expressions in tumours. This analysis is used to weigh up the treatment options for patients who have cancer, for example. The certainty ...
Jul 14, 2014
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Adult stem cells and cancer cells have many things in common, including an ability to migrate through tiny gaps in tissue. Both types of cells also experience a trade-off when it comes to this ability; having a flexible nucleus ...
Feb 25, 2014
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Incorrectly positioned nuclei are not merely a sign but a possible cause of human congenital myopathies, a string of inherited muscle diseases, Victoria Schulman, graduate student at Weill Cornell Graduate School of Medical ...
Dec 16, 2013
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