Drug combination shows benefit in RAS-driven cancers
Cancers driven by the RAS oncogene are aggressive and difficult to treat, and thus far precision drugs haven't been able to target the mutant RAS gene successfully.
Apr 3, 2017
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Cancers driven by the RAS oncogene are aggressive and difficult to treat, and thus far precision drugs haven't been able to target the mutant RAS gene successfully.
Apr 3, 2017
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By the time Ewing's Sarcoma is diagnosed, primarily in teens and young adults, it has often spread from its primary site to other parts of the body, making it difficult to treat. A University of Colorado Cancer Center study ...
Mar 24, 2017
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In a study published in the scientific journal Oncotarget, researchers from Uppsala University show how the protein EZH2 affects the development of multiple myeloma, and that inhibition of EZH2 could be used as a new strategy ...
Jan 12, 2017
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Molecular analysis of a tumor biopsy from a proto-oncogene 1 receptor tyrosine kinase positive (ROS1+) patient with acquired crizotinib resistance revealed a novel mutation in the v-kit Hardy Zuckerman 4 feline sarcoma viral ...
Apr 11, 2016
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In a finding with enormous implications for cancer diagnostics and therapeutics, Whitehead Institute scientists have discovered that breaches in looping chromosomal structures known as "insulated neighborhoods" can activate ...
Mar 3, 2016
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For the first time, researchers have shown that an enzyme key to regulating gene expression—and also an oncogene when mutated—is critical for the expression of numerous inflammatory compounds that have been implicated ...
Feb 3, 2016
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Proteins are like bricks that form our cells and they are built by the orders given by our genetic material, DNA. In human diseases, eventually DNA alterations modify proteins and they don't do their normal function, either ...
Dec 16, 2015
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A team of Singapore based scientists have found that pairing a new approach with an old drug may be an effective approach to treat common cancers. In a landmark study, Professor David Virshup and Dr. Jit Kong Cheong, from ...
Mar 23, 2015
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Researchers led by a team at the University of Illinois at Chicago, have identified a novel role for a signaling mechanism in lung cells that permanently places them into a state of suspended animation called senescence. ...
Mar 2, 2015
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An interdisciplinary team of chemists, oncologists and one statistician at Stanford has taken the first step toward developing a technique that can identify the origin of certain types of cancer—a potential boon to doctors ...
Jul 11, 2014
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