For patients managing cancer and other chronic health issues, painkillers such as morphine and Vicodin are often essential for pain relief. The body's natural tendency to develop tolerance to these medications, however, often ...
Jun 10, 2013
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Feeling full involves more than just the uncomfortable sensation that your waistband is getting tight. Investigators reporting online on July 5th in the Cell Press journal Cell have now mapped out the signals that travel ...
Jul 5, 2012
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Researchers at the University of Montreal's Sainte-Justine Hospital have identified how neural cells like those in our bodies are able to build up resistance to opioid pain drugs within hours. Humans have known about the ...
Apr 3, 2012
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A University of Colorado Boulder-led research team has discovered that two protein receptors in the central nervous system team up to respond to morphine and cause unwanted neuroinflammation, a finding with implications for ...
Apr 2, 2012
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At the molecular level, drugs like salvinorin A (the active ingredient of the hallucinogenic plant Salvia divinorum) work by activating specific proteins, known as receptors, in the brain and body. Salvinorin A, the most ...
Mar 21, 2012
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Nearly everyone who has tried to quit smoking says it's incredibly difficult, and the struggle is due in part to genetic factors. Now, a new study from the Raymond and Ruth Perelman School of Medicine at the University of ...
May 16, 2011
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The herbal substance kratom, derived from the leaves of a Southeast Asian tree, is used by nearly 2 million people in the United States annually. It can be easily purchased at gas stations and convenience stores, smoke shops ...
Feb 21, 2024
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Opioids such as morphine are the gold standard for treating cancer-induced bone pain, but new University of Arizona Health Sciences research published in the journal Pain uncovers a mechanism by which chronic morphine use ...
Jul 6, 2023
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In the United States, federal legislation mandates that all states track data on all newborns who have been exposed to substances during pregnancy and ensure that a plan of Safe Care is created for each family. Yet each state ...
May 31, 2023
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A new therapeutic designed by Scripps Research chemists can alter the molecular structure of the potent opioid carfentanil, inactivating the opioid and reversing a carfentanil overdose. The compound, which is described in ...
Apr 17, 2023
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