Roughly a third of all drugs approved by the U.S. Food and Drug Administration target a large family of biomolecules, known as G protein-coupled receptors (GPCRs), whose job is to trigger cellular responses to extracellular ...
Apr 27, 2022
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You're startled by a threatening sound, and your breath quickens. You smash your elbow and pant in pain. Why does your breathing rate increase dramatically when you're hurting or anxious?
Jan 21, 2022
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Scientists at Scripps Research in Florida have created a collection of new pain-relieving compounds, that like morphine and other drugs, provide relief via activation of opioid receptors, but without inducing many dangerous ...
Nov 22, 2021
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Data from a nationally representative survey indicate that in 2019, nearly three-fourths of U.S. adults reporting buprenorphine use did not misuse the medication in the past 12 months. In addition, buprenorphine misuse among ...
Oct 15, 2021
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Opioid receptors are proteins in the central nervous system that are targeted by opioid drugs for pain relief. There are three subtypes of opioid receptors, MOP, DOP and KOP, in addition to the opioid-related NOP receptor.
Opioids are a class of substances that control sensations such as pain and emotions in animals. While plant-derived opioid narcotics such as morphine are the most well-recognized, other opioid molecules like endorphins can ...
Oct 1, 2021
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It's long been known that opioid overdose deaths are caused by disrupted breathing, but the actual mechanism by which these drugs suppress respiration was not understood. Now, a new study by Salk scientists has identified ...
Aug 13, 2021
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Mice exposed to the opioid oxycodone before birth experience permanent changes in behavior and gene expression. The new research published in eNeuro highlights a need to develop safer types of painkillers for pregnant women.
Jul 26, 2021
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Building on their previous findings, scientists from the Immuno-Pharmacology and Interactomics group at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH), in collaboration with the Center ...
Jun 3, 2021
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Fentanyl, oxycodone, morphine—these substances are familiar to many as a source of both pain relief and the cause of a painful epidemic of addiction and death.
Apr 24, 2021
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