Diseases, Conditions, Syndromes

Serendipity opens new path toward osteoporosis treatment

A cellular protein whose normal function appears to suppress bone formation may be a potential new target for treating osteoporosis, according to a collaborative study led by Weill Cornell Medicine and NewYork-Presbyterian ...

Oncology & Cancer

Bone cells suppress cancer metastases

In breast cancer, there are cases of women and men whose cancer returns in their bones 20-30 years after they were treated for their primary disease and thought they were cancer-free. This phenomenon always puzzled Jefferson ...

Diseases, Conditions, Syndromes

New osteoporosis drug combination outperforms current alternatives

A combination of two FDA-approved osteoporosis drugs with different mechanisms of action was found to increase bone density better than treatment with either drug alone in a small clinical trial. As reported in paper receiving ...

Medical research

Pituitary hormone TSH found to directly influence bone growth

Researchers at Mount Sinai School of Medicine have found that thyroid-stimulating hormone (TSH), a hormone produced in the anterior pituitary gland that regulates endocrine function in the thyroid gland, can promote bone ...

Diseases, Conditions, Syndromes

New mechanism activates bone-building cells in osteoperosis

The number of osteoporosis medications that promote bone formation are few compared to those that suppress bone resorption. A research group led by Kumamoto University scientists has discovered that the gene SIRT7 is important ...

Medical research

Scientist takes next step in search for bone disease treatment

For more than a decade, Hiranmoy Das, Ph.D., has been investigating how Kruppel-like Factor 2 (KLF2), a gene that codes protein into a specific human chromosome, influences the development of bone and musculoskeletal diseases ...

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