Medical research
Researchers pinpoint how smoking causes osteoporosis
(Medical Xpress)—Human bone breaks down and regenerates naturally all the time, in a perfectly balanced dance that maintains skeletal integrity.
Jun 19, 2013
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Page 2 - News tagged with osteoclast
Medical research
New study reveals key protein that could help prevent excessive bone loss in osteoporosis
Osteoporosis, a condition characterized by porous and fragile bones, poses a significant threat to skeletal health. As the very framework of the human body, bones provide crucial structural support. When bone mass diminishes, ...
May 30, 2024
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Medications
Drug that kills off sleeping bone cells could treat lower back pain
An existing drug that targets senescent, or sleeping cells could provide the answer to treating lower back pain, according to a new study.
Nov 14, 2023
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Medical research
Study links blood marker to risk of osteoporotic hip fracture in men
Bone health requires a balanced activity of various bone cell types including bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoporosis occurs when osteoclasts dominate without adequate bone formation to compensate. ...
Aug 17, 2022
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Immunology
Double-stranded RNA induces bone loss during gum disease
Tokyo University of Agriculture and Technology researchers reported on a new discovery regarding the mechanisms for bone loss in gum disease (periodontitis). They found that double stranded RNA molecules can activate the ...
Apr 8, 2022
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Genetics
Impaired immune response may cause bone resorption in patients with genetic disorder
A research team led by Hiroshima University Professor Satoshi Okada has determined that enhanced bone resorption activity due to a faulty immune response may underpin multifocal osteomyelitis—painful, chronic bone infections—in ...
Sep 8, 2021
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Medical research
New type of bone cell could reveal targets for osteoporosis treatment
Researchers at the Garvan Institute of Medical Research have discovered a new type of bone cell that may reveal new therapeutic approaches for osteoporosis and other skeletal diseases.
Feb 25, 2021
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Medical research
Messages sent by osteoblasts to osteoclasts are enclosed in an extracellular vesicle
In a study published recently in Communications Biology, researchers led by Kanazawa University explain how a tiny fish could help end painful metabolic and genetic bone diseases.
Jul 14, 2020
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Medical research
Understanding how bone-dissolving cells are generated
Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones. But the intracellular mechanisms through which macrophages ...
Jun 10, 2020
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Medical research
Arginine depletion as a starting point for potential rheumatoid arthritis treatments
Rheumatoid arthritis is a common inflammatory joint disease. A feature of this disease is the increased fusion of endogenous immune cells (macrophages) to form so-called osteoclasts, which attack and break down bone tissue.
Jan 23, 2020
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