Failure of hormone deprivation therapy, which is used to slow prostate cancer in patients, leads to castration-resistant prostate cancer, a lethal form of advanced disease with limited treatment options.
Mar 10, 2017
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26
A poor diet might be damaging more than your waistline—it might be leading to cognitive decline and poor memory, according to Western-led research released this week.
Jun 5, 2019
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30
The classes of RNA molecules encoded by DNA sequences previously considered non functional may play a vital role in cell stress responses, and could one day lead to cancer treatments. A*STAR researchers have identified a ...
Jan 20, 2016
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63
A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations ...
Mar 5, 2021
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101
In an analysis of how regulators review pesticides for their potential to cause cancer, researchers at Silent Spring Institute identified more than two dozen registered pesticides that were linked with mammary gland tumors ...
Aug 4, 2020
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540
In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes ...
Feb 15, 2023
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48
Insulin levels rise after eating a meal, signaling uptake of circulating glucose by skeletal muscle. In individuals with diabetes this process is often impaired—a condition known as insulin resistance.
Oct 17, 2018
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8
Researchers at Case Western Reserve University and University Hospitals have identified an enzyme that blocks insulin produced in the body—a discovery that could provide a new target to treat diabetes.
Dec 8, 2023
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20
Cancer cells defy the rules by which normal cells abide. They can divide without cease, invade distant tissues and consume glucose at abnormal rates.
Jul 8, 2015
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212
It's safe to slap on the sunscreen this summer – in repeated doses – despite what you have read about the potential toxicity of sunscreens.
Nov 21, 2018
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