The gene p53 functions normally as a cancer suppressor, but mutated versions of the gene have been implicated in the development and growth of nearly half of all human cancers. Now, for the first time, scientists at VCU Massey ...
Jun 14, 2017
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Directly injecting a tumor with an agent that activates a natural, powerful tumor suppressor enhances the drug's capacity to attack the tumor both locally and where it spreads, scientists report in the journal Cancer Research.
May 22, 2017
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Duke Cancer Institute scientists have described a previously unknown series of steps that cells undergo when stressed, adding crucial information to the understanding of DNA damage that is at the heart of research into aging ...
Apr 5, 2017
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The gene p53 is the most commonly mutated gene in cancer - it is p53's job to monitor cells for DNA damage and to mark damaged cells for destruction and so cancer cells with mutated DNA must disable p53 before it disables ...
Apr 3, 2017
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Scientists at The Wistar Institute in collaboration with Roswell Park Cancer Institute found a significant association between a rare genetic variant of the p53 gene present in African American women and their risk of developing ...
Feb 27, 2017
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Tumor suppressors stop healthy cells from becoming cancerous. Researchers from Charité - Universitätsmedizin Berlin, the Medical University of Graz and the German Institute of Human Nutrition in Potsdam-Rehbruecke have ...
Dec 21, 2016
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Could limiting food intake be a valid treatment strategy for certain types of cancers? New research in The FASEB Journal suggests "maybe." In a report appearing online in The FASEB Journal, scientists show that food restriction ...
Nov 16, 2016
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A new drug could be used to treat one of the most aggressive forms of breast cancer, a research centre based at University College Dublin and St Vincent's Hospital has discovered.
Nov 2, 2016
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Proteins that bind DNA or RNA are usually put in different categories, but researchers at Umeå University in Sweden and Inserm in France recently showed how the p53 protein has the capacity to bind both and how this controls ...
Aug 4, 2016
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Metformin, a medication routinely used by millions of people with type 2 diabetes, may also play an unexpected role in blocking a significant cause of preterm birth, according to research findings published July 25.
Jul 25, 2016
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