Oxford University epidemiologist Richard Peto was puzzled by a paradox: If cancer is a function of individual cells going haywire, wouldn't an organism with a lot more cells, say a whale, have a greater chance of getting ...
Aug 28, 2019
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Cancer is a multidisciplinary disease, with different mutations leading to different prognoses and treatment necessities. Among the most important mutation targets in cancers, affecting more than 50 percent of all cancer ...
Jan 15, 2019
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A new innovation in cancer research will enable scientists to understand the complex causes of the disease with unprecedented speed and sophistication. This will accelerate the development of new and better treatments, and ...
Oct 18, 2018
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University of Toronto researchers have shone light on a well-known but mysterious gene that plays a key role in the growth of cancer.
Aug 29, 2018
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Researchers at the Federal University of Rio de Janeiro (UFRJ) and the State University of Rio de Janeiro (UERJ) have made a discovery that could lead to the development of a treatment against more than half of breast cancer ...
Jun 27, 2018
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Scientists at The Wistar Institute have found a novel mechanism through which mutant p53 enhances metastasis by controlling tumor metabolism. The research, published online in Genes & Development, also revealed how this process ...
Feb 26, 2018
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Regenerative medicine using human pluripotent stem cells to grow transplantable tissue outside the body carries the promise to treat a range of intractable disorders, such as diabetes and Parkinson's disease.
Apr 26, 2017
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Individuals with Li-Fraumeni syndrome are at an increased risk for a number of cancers, including breast and bone cancer. Li-Fraumeni syndrome is an inherited cancer disorder caused by mutations in the tumor suppressing protein ...
Nov 21, 2016
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Using microsecond timescale molecular dynamics simulations, a new study published in Scientific Reports reveals p53 weak spots and sheds light on the protein instability, which is linked to its tendency to aggregate and form ...
Sep 7, 2016
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The gene p53 has been described as the "guardian of the genome" due to its prominent role in preventing genetic mutations. More than half of all cancers are thought to originate from p53 mutations or loss of function, and ...
Dec 14, 2015
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