Researchers at Mount Sinai School of Medicine, the University of Manchester, and the MD Anderson Cancer Center have found a new role for an oncogenic signaling pathway in embryonic stem cell (ESC) self-renewal and in reprogramming ...
Aug 3, 2012
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Women with cancer-causing strains of human papillomavirus (HPV) may be at increased risk for cardiovascular disease (CVD) and stroke even when no conventional risk factors for CVD are present.
Oct 24, 2011
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Researchers at the Stanford University School of Medicine have untangled two distinct ways in which a common, naturally occurring "tumor-suppressor" protein works. The separation of these two functions — which can have ...
May 12, 2011
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Proteins that are frequently altered in tumors play a prominent role in cancer research. The protein RFX7, a largely unknown transcription factor, has recently been linked to lymph node cancer. Researchers at the Leibniz ...
Jul 19, 2022
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A team of researchers at the University of Michigan Rogel Cancer Center were the first to generate a bona fide mouse model of a Merkel cell carcinoma, a rare and potentially aggressive form of skin cancer. The study outlining ...
Jun 15, 2022
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Chronic inflammatory bowel disease (IBD) are inflammations of the gastrointestinal tract which flare up in phases and are accompanied by bloody bowel movements, diarrhea and severe impairment of the quality of life. IBD patients ...
Nov 1, 2021
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The development of pancreatic cancer is driven by co-existing mutations in an oncogene involved in controlling cell growth, called KRAS, and in a tumor suppressor gene, called p53. But how these mutations cooperate to promote ...
Jun 18, 2020
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Cutaneous squamous cell carcinoma (cuSCC) is the second most common diagnosed malignancy in the United States, with approximately 700,000 new cases each year. Cumulative exposure to ultraviolet light is the primary environmental ...
Mar 30, 2020
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Lack of oxygen, or hypoxia, is a biological stressor that occurs under various conditions such as wound healing and stroke. To rescue the tissue, the body has innate mechanisms that "kick in" to make the cells of the hypoxic ...
Sep 19, 2019
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Oxford University epidemiologist Richard Peto was puzzled by a paradox: If cancer is a function of individual cells going haywire, wouldn't an organism with a lot more cells, say a whale, have a greater chance of getting ...
Aug 28, 2019
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