Neuroscience

Enhancing mechanism of capsaicin-evoked pain sensation

Drs. Takayama and Tominaga in National Institute for Physiological Sciences (NIPS) (Okazaki Institute for Integrative Bioscience) clarified that an interaction between capsaicin receptor TRPV1 and chloride channel anoctamin ...

Neuroscience

Spinal cord neurons that control pain and itch

The spinal cord transmits pain signals to the brain, where they are consciously perceived. But not all the impulses arrive at their destination: Certain neurons act as checkpoints and determine whether a pain signal is relayed ...

Neuroscience

Neuroscience: Why scratching makes you itch more

Turns out your mom was right: Scratching an itch only makes it worse. New research from scientists at Washington University School of Medicine in St. Louis indicates that scratching causes the brain to release serotonin, ...

Neuroscience

Researchers find new target for chronic pain treatment

Researchers at the UNC School of Medicine have found a new target for treating chronic pain: an enzyme called PIP5K1C. In a paper published today in the journal Neuron, a team of researchers led by Mark Zylka, PhD, Associate ...

Neuroscience

Researchers identify innate channel that protects against pain

Scientists have identified a channel present in many pain detecting sensory neurons that acts as a 'brake', limiting spontaneous pain. It is hoped that the new research, published today [22 January] in the Journal of Neuroscience, ...

Medical research

Bacteria make us feel pain... and suppress our immune response

The pain of invasive skin infections caused by methicillin-resistant Staphylococcus aureus, and possibly other serious, painful infections, appear to be induced by the invading bacteria themselves, and not by the body's immune ...

Medical research

Putting the brakes on pain

Neuropathic pain—pain that results from a malfunction in the nervous system—is a daily reality for millions of Americans. Unlike normal pain, it doesn't go away after the stimulus that provoked it ends, and it also behaves ...

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