(HealthDay)—Curcumin can resensitize chemoresistant pancreatic ductal adenocarcinoma (PDAC) cells through inhibition of the polycomb repressive complex 2 (PRC2)-PVT1-c-Myc axis, according to a study published online July ...
Aug 2, 2017
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Cells, just like people, have memories. They retain molecular markers that at the beginning of their existence helped guide their development. Cells that become cancerous may be making use of these early memories to power ...
Jul 27, 2017
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Pancreatic cancer, most frequently pancreatic ductal adenocarcinoma (PDAC), is the most lethal and aggressive of all cancers. Unfortunately, there are not many effective therapies available other than surgery, and that is ...
Apr 10, 2017
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A protein known as arginine methyltransferase 1 (PRMT1) may be a potential therapeutic target for pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer, and one of the most deadliest with a less ...
Mar 28, 2017
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Researchers have moved an important step closer to understanding why pancreatic cancer is so hard to treat. With a median survival of only 6 months and a 5-year survival rate of about 8%, patients tend to be diagnosed when ...
Feb 23, 2017
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Conventional, high-dose chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors' recurrence in more aggressive forms, researchers at Taipei Medical University ...
Nov 23, 2016
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Internal conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer. Curbing this infighting has the potential to make treatment more effective, according to a study led ...
Aug 25, 2016
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Massachusetts General Hospital (MGH) investigators have discovered the mechanism by which obesity increases inflammation and desmoplasia - an accumulation of connective tissue - in the most common form of pancreatic cancer. ...
Jul 6, 2016
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Researchers have identified a new way to tailor treatments for patients with pancreatic cancer, one of the most deadly forms of cancer. Currently only five per cent of people with pancreatic cancer survive longer than five ...
Jun 14, 2016
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Massachusetts General Hospital (MGH) investigators have identified the first potential molecular treatment target for the most common form of pancreatic cancer, which kills more than 90 percent of patients. Along with finding ...
May 12, 2016
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