Oncology & Cancer
Removal of gene prevents development of pancreatic cancer in mice
The action of a gene called ATDC is required for the development of pancreatic cancer, a new study finds.
May 2, 2019
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Genetics
Rare genetic change provides clues to pancreas development
Researchers have discovered a key clue into the development of the pancreas and brain by studying rare patients born without a pancreas. The study from the Wellcome Sanger Institute, the University of Exeter and collaborators ...
Apr 18, 2019
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Oncology & Cancer
New study targets Achilles' heel of pancreatic cancer, with promising results
Advanced pancreatic cancer is often symptomless, leading to late diagnosis only after metastases have spread throughout the body. Additionally, tumor cells are encased in a "protective shield," a microenvironment conferring ...
Apr 17, 2019
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Medical research
The fluid that feeds tumor cells
Before being tested in animals or humans, most cancer drugs are evaluated in tumor cells grown in a lab dish. However, in recent years, there has been a growing realization that the environment in which these cells are grown ...
Apr 16, 2019
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Medical research
Researchers succeed at removing some types of pancreatic cancer in animal models
Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National Cancer Research Centre (CNIO), have published in Cancer Cell the results of a study that shows full regression of advanced ...
Apr 12, 2019
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Oncology & Cancer
New, revised topics released in ACR appropriateness criteria
(HealthDay)—The latest edition of the American College of Radiology (ACR) Appropriateness Criteria has been released and includes 188 diagnostic imaging and interventional radiology topics, with 908 clinical variants covering ...
Apr 9, 2019
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Oncology & Cancer
Genome-wide analysis reveals new strategies to target pancreatic cancer
For some cancers, initial treatment with chemotherapy brings positive, but only temporary, results: tumors shrink, but then rebound as the cancer becomes drug-resistant. This pattern of remission-resistance-relapse is particularly ...
Apr 4, 2019
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Oncology & Cancer
Adavosertib speeds cancer cells into the wall of mitotic catastrophe
A cancer cell is like a racecar, speeding through the process of cellular replication. But it has to stop at the G2M cell cycle checkpoint, where a race inspector called Wee1 checks it over for damage—cells with intact ...
Apr 1, 2019
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Oncology & Cancer
New potential therapeutic target for pancreatic cancer discovered
Cancer cells demand enormous amounts of molecular "food" to survive and grow, and a study published March 27 online in Nature by researchers at The University of Texas MD Anderson Cancer Center may have identified a new approach ...
Mar 27, 2019
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Oncology & Cancer
Tumor-associated immune cells hinder frontline chemotherapy drug in pancreatic cancer
A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action, research led by the University of ...
Mar 26, 2019
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