Before being tested in animals or humans, most cancer drugs are evaluated in tumor cells grown in a lab dish. However, in recent years, there has been a growing realization that the environment in which these cells are grown ...
Apr 16, 2019
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Researchers have found that a protein called SLC6A14 is overexpressed by several fold in pancreatic tumors taken from patients and in cancerous pancreatic cells lines compared with normal pancreatic tissue or normal pancreatic ...
Oct 17, 2016
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The results of an early-stage (phase 1b) clinical trial for pancreatic cancer show that an experimental therapy can control tumors well enough to make some patients eligible for surgery, according to data published in The ...
Apr 4, 2016
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Seeing a chance to stop one of the most deadly kinds of cancer before it forms, doctors at hospitals around the nation are focusing on the common pancreatic cyst.
Jul 22, 2011
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A synthetic derivative of vitamin D was found by Salk Institute researchers to collapse the barrier of cells shielding pancreatic tumors, making this seemingly impenetrable cancer much more susceptible to therapeutic drugs.
Sep 25, 2014
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Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a combination of two anti-cancer compounds that shrank pancreatic tumors in mice—supporting the immediate evaluation of the drugs in a clinical ...
Nov 18, 2019
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With Alex Trebek's recent announcement that his pancreatic cancer is in remission, many people have wondered if this difficult cancer is now easier to treat. Pancreatic cancer remains a major cancer killer, but advances are ...
May 31, 2019
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Researchers have moved an important step closer to understanding why pancreatic cancer is so hard to treat. With a median survival of only 6 months and a 5-year survival rate of about 8%, patients tend to be diagnosed when ...
Feb 23, 2017
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How a person's immune system interacts with tumor cells influences how cancer progresses and can explain why treatment causes tumors to shrink for some patients but not others. Yale researchers have developed a new method ...
Aug 4, 2023
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A compound discovered at Sanford Burnham Prebys Medical Discovery Institute (SBP) has advanced into a Phase 1 trial for metastatic pancreatic cancer. Called CEND-1 (scientifically known as iRGD), the compound was exclusively ...
Aug 21, 2018
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