Study suggests way to improve treatment of hereditary breast cancer
PARP inhibitors have improved survival of breast cancer patients with BRCA1/2 mutations, but the drugs eventually stop working and the cancer returns.
Aug 15, 2024
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PARP inhibitors have improved survival of breast cancer patients with BRCA1/2 mutations, but the drugs eventually stop working and the cancer returns.
Aug 15, 2024
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St. Jude Children's Research Hospital scientists report the first successful treatment of a pediatric patient with high-risk refractory neuroblastoma using a targeted therapy guided by clinical genomics.
Aug 15, 2024
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A research team led by Professor Ying Wai Chan from the School of Biological Sciences at The University of Hong Kong (HKU) has made a significant breakthrough in understanding how cancer cells develop resistance to a class ...
Jul 31, 2024
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Researchers at The Institute of Cancer Research, London, have increased our understanding of how a cancer drug called a PARP inhibitor stops working in women with breast cancer that has spread. This research could ultimately ...
May 8, 2024
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Patient prognosis and treatment response prediction are key factors in treating ovarian cancer, which is characterized by the lowest survival rate among gynecological cancers. Consequently, there is strong demand for a more ...
Apr 15, 2024
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The first-in-class PARP1-selective inhibitor saruparib demonstrated encouraging early efficacy and a favorable safety profile in patients with homologous recombination repair (HRR)-deficient breast cancers, according to results ...
Apr 8, 2024
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Triple negative breast cancer is the most aggressive subtype of the disease and is notorious for a poor prognosis, but scientists are working on a breakthrough method of converting these treatment-resistant tumors into a ...
The results of a multisite clinical trial overseen by University of Colorado Cancer Center member Bradley Corr, MD, could offer new hope to patients with metastatic and recurrent uterine cancer, also known as endometrial ...
Mar 20, 2024
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Some anti-cancer treatments not only target tumor cells but also healthy cells. If their effects on the latter are too strong, their use can become limiting.
Mar 20, 2024
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Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators. They have conducted the first whole genome sequencing ...
Mar 4, 2024
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