A new study led by University of California, Irvine researchers has confirmed a link between altered DNA repair and increased DNA damage associated with spinocerebellar ataxia type 7 (SCA7), a debilitating, sometimes deadly ...
Nov 30, 2021
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The results of a multisite clinical trial overseen by University of Colorado Cancer Center member Bradley Corr, MD, could offer new hope to patients with metastatic and recurrent uterine cancer, also known as endometrial ...
Mar 20, 2024
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July 24, 2019—A new molecular mechanism discovered by UT Southwestern researchers indicates that drugs currently used to treat less than 10 percent of breast cancer patients could have broader effectiveness in treating ...
Jul 24, 2019
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A newly discovered function of PARP-1 could be the key to more effective therapeutics to treat advanced prostate cancer patients, a recent preclinical study published in Cancer Discovery by Jefferson's Kimmel Cancer Center ...
Oct 9, 2012
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Maintenance treatment with the PARP inhibitor rucaparib (Rubraca) was well tolerated and provided clinical responses among patients with advanced BRCA- or PALB2-mutated pancreatic cancer sensitive to platinum-based chemotherapy, ...
Apr 2, 2019
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Researchers have identified genetic tests that predict which cancer patients may benefit from the drugs in combination with chemotherapy.
Nov 6, 2023
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New data from the Phase III EMBRACA trial led by researchers at The University of Texas MD Anderson Cancer Center found the PARP inhibitor talazoparib did not demonstrate a statistically significant overall survival (OS) ...
Apr 27, 2020
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Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells—and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast ...
May 19, 2021
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New research that uncovers the mechanism behind the newest generation of cancer drugs is opening the door for better targeted therapy.
Jul 8, 2019
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Leiomyosarcoma is a type of soft tissue sarcoma that is hard to treat and associated with a poor prognosis. Scientists at the Institute of Cancer Research are working to better understand the biology of this cancer to develop ...
Jul 25, 2023
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