The results of a multisite clinical trial overseen by University of Colorado Cancer Center member Bradley Corr, MD, could offer new hope to patients with metastatic and recurrent uterine cancer, also known as endometrial ...
Mar 20, 2024
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Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators. They have conducted the first whole genome sequencing ...
Mar 4, 2024
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Researchers have identified genetic tests that predict which cancer patients may benefit from the drugs in combination with chemotherapy.
Nov 6, 2023
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Researchers at Baylor College of Medicine have developed a new compound called d16 that can reduce tumor growth and overcome therapeutic resistance in mutant p53-bearing cancers in the lab. The findings, published in the ...
Sep 27, 2023
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Leiomyosarcoma is a type of soft tissue sarcoma that is hard to treat and associated with a poor prognosis. Scientists at the Institute of Cancer Research are working to better understand the biology of this cancer to develop ...
Jul 25, 2023
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Advanced estrogen receptor-positive (ER+) breast cancer can be especially difficult to treat. A new study by researchers at Dartmouth Cancer Center led by Todd W. Miller, Ph.D., shows promise in using a combination of estrogen ...
Jul 13, 2023
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Homologous Recombination Deficiency (HRD) is a biomarker that predicts ovarian cancer treatment with PARP inhibitors or breast cancer treatment with first-line platinum-based chemotherapy. However, limited research is documented ...
Apr 25, 2023
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Despite recent advances, ovarian cancer remains the fifth leading cause of cancer-related deaths among women, and there's a critical need for new treatment options, especially for advanced cancers that grow back after standard ...
Apr 17, 2023
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Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive. To identify previously unknown genes ...
Apr 4, 2023
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A rapid genetic testing model for patients with advanced prostate cancer can more quickly identify those with "actionable" gene variants eligible for newer targeted therapies, reports a clinical trial in The Journal of Urology.
Mar 29, 2023
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