Immunology

Atopic dermatitis severity tied to IgG response to S. aureus

(HealthDay)—Atopic dermatitis (AD) disease severity is associated with immunoglobulin G (IgG) responses against Staphylococcus aureus antigens, according to a study published online Nov. 30 in the British Journal of Dermatology.

HIV & AIDS

Researchers identify a new HIV reservoir

HIV cure research to date has focused on clearing the virus from T cells, a type of white blood cell that is an essential part of the immune system. Yet investigators in the Division of Infectious Diseases at the University ...

HIV & AIDS

HIV expert's studies yielding insights into diseases of aging

While AIDS originally was seen as an adaptive immune disease, the research of Alan Landay, PhD, has contributed to a view of it as a cell driven-inflammation linked to immunosenescence—the gradual deterioration of the immune ...

Oncology & Cancer

Disturbances in blood cell gene transcription may lead to leukemia

Researchers have succeeded in shedding light on the pathogenesis of DNA breakpoints that are associated with leukemia. A mechanism discovered in a recent study can explain up to 90% of DNA damages present in the most common ...

Alzheimer's disease & dementia

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in the March 30 issue of Science ...

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Pathogenesis

The pathogenesis of a disease is the mechanism by which the disease is caused. The term can also be used to describe the origin and development of the disease and whether it is acute, chronic or recurrent. The word comes from the Greek pathos, "disease", and genesis, "creation".

Types of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown.

Most diseases are caused by multiple pathogenetical processes together. For example, certain cancers arise from dysfunction of the immune system (skin tumors and lymphoma after a renal transplant, which requires immunosuppression).

Often, a potential etiology is identified by epidemiological observations before a pathological link can be drawn between the cause and the disease.

This text uses material from Wikipedia, licensed under CC BY-SA