Diseases, Conditions, Syndromes

How are dreaded multidrug-resistant pathogens brought into hospitals?

According to National Reference Center for Surveillance of Nosocomial Infections esti-mates, up to 15,000 patients die of hospital-acquired infections in Germany every year. Here, multidrug-resistant bacteria, against which ...

Medical research

Video: CRISPR puts up a fight against persistent herpesviruses

Since its development, CRISPR technology has been applied a range of scientific inquiries, spanning from the genomic editing of Florida orange crops to Zebrafish. In work recently published in PLOS Pathogens, Robert Jan Lebbink ...

Immunology

Discovery of a new defense system against microbial pathogens

For the first time in the world, a group of researchers discovered a human immune receptor, which detects the invasion of pathogenic microorganisms. They thereby succeeded in identifying a so far unknown host defense mechanism. ...

Immunology

Immunologist's book offers blueprint for medical revolution

Rodney Dietert, Cornell professor of immunotoxicology, has penned a new book, "The Human Superorganism: How the Microbiome Is Revolutionizing the Pursuit of a Healthy Life" (Dutton, 2016), that calls for a new paradigm in ...

Diseases, Conditions, Syndromes

Colistin-resistant gene detected in the US for the second time

For the second time, a clinical isolate of a bacterial pathogen has been detected in humans in the United States which carries the colistin resistance gene, mcr-1. This may also be the first case to show up in the US. That ...

Medical research

How tumor necrosis factor protects against infection

Tumour necrosis factor (TNF), a messenger substance in the immune system, plays an important role in triggering chronic inflammatory diseases. For this reason, TNF inhibitors are a standard form of treatment for patients ...

Medical research

A new wave of antimalarial drugs

Malaria caused by the parasite Plasmodium falciparum remains a major public health problem worldwide. As a continuation of previous research targeting Hsp90, a universal molecular chaperone performing vital functions both ...

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