Genetics

New gene correction therapy for Duchenne muscular dystrophy

Duchenne type muscular dystrophy (DMD) is the most common hereditary muscular disease among children, leaving them wheelchair-bound before the age of 12 and reducing life expectancy. Researchers at Technical University of ...

Medications

New approach to pain treatment in diseases of the pancreas

One of the worst symptoms associated with inflammation or cancer of the pancreas is severe chronic pain. Pancreatic pain is difficult to treat, because many painkillers prove ineffective in pancreatic patients. In a recent ...

Genetics

Crime scene schizophrenia—30 genes under suspicion

The research group led by Prof. Alex Schier, director of the University of Basel's Biozentrum, has identified 30 genes associated with schizophrenia. The team was able to show which pathological changes in the brain and behavioral ...

Diseases, Conditions, Syndromes

Mechanism of fibrosis development discovered

Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease of unknown origin with limited treatment options. Research suggests that the signaling molecule WNT5A plays a key role in the pathogenic process. Now, a group ...

Diseases, Conditions, Syndromes

Genetic studies and MRI scans shed light on low back pain

By delving into the mysteries of low back pain, scientists have identified three genes linked to chronic back pain and proposed the order in which pathological changes to the spine lead to low back pain.

Cardiology

MicroRNA molecule can cause pathological changes in the heart

Cardiac fibrosis involves an increase of connective tissue in the cardiac muscle, causing a loss of function. A team of researchers at the Technical University of Munich (TUM) has now discovered that microRNA 29 (miR-29) ...

Ophthalmology

Brain diseases manifest in the retina of the eye

Diseases of the central nervous system (CNS) may manifest as pathological changes in the retina of the eye. Research from the University of Eastern Finland (UEF) shows that retinal changes may be detected earlier than brain ...

Alzheimer's disease & dementia

Inflammatory changes in the brain twenty years before Alzheimer onset

Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, according to a new study from Karolinska Institutet published in the medical scientific journal ...

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