Researchers at the University of Pittsburgh School of Medicine have uncovered a major reason why the Parkinson's-related protein alpha-synuclein, a major constituent of the Lewy bodies that are the pathological hallmark of ...
Jun 8, 2016
0
354
Parkinson's disease (PD), a chronic, progressive and devastating neurodegenerative motor disease affecting as many as one million Americans, is complex. Its causes likely include a combination of genetic, environmental and ...
May 19, 2016
0
103
As stem cell-based therapies are moving rapidly towards clinical trials, treatments for Parkinson's Disease (PD), an incurable condition, may be on the horizon. A recent announcement of a Phase I/IIa clinical trial involving ...
Mar 29, 2016
0
24
Many patients with Parkinson's Disease (PD) develop mild cognitive impairment (MCI) or dementia. Identifying biomarkers for cognitive impairment could be instrumental in facilitating both early diagnosis of MCI and developing ...
Feb 17, 2016
0
112
Recent evidence has shown a greater risk of dementia, in particular Alzheimer's disease (AD), in individuals using anticholinergic medications regularly. These drugs are widely used by older adults to treat bladder dysfunction, ...
Jan 4, 2016
0
8
Parkinson's Disease (PD) patients have a five-fold greater risk of carrying genetic mutations in the β-glucocerebrosidase gene (GBA), which are commonly associated with Gaucher disease (GD). Patients with both PD and GD ...
Nov 10, 2015
0
43
An estimated seven to ten million people worldwide are living with Parkinson's disease (PD), which is an incurable and progressive disease of the nervous system affecting movement and cognitive function. More than half of ...
Oct 9, 2015
0
43
About 50% of patients with Parkinson's disease (PD) experience freezing of gait (FOG), an inability to move forward while walking. This can affect not only mobility but also balance. In a new study published in Restorative ...
Aug 31, 2015
0
34
Low-dose lithium reduced involuntary motor movements - the troubling side effect of the medication most commonly used to treat Parkinson's disease (PD) - in a mouse model of the condition that is diagnosed in about 60,000 ...
Jul 27, 2015
0
36
In recent years, an important Parkinson's disease (PD) research focus has been on gut-related pathology, pathophysiology, and symptoms. Gastrointestinal dysfunction, in particular constipation, affects up to 80% of PD patients ...
Jun 23, 2015
0
129
